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ABOUT US

Partners

PARTNERS

CREATIVE is jointly led by Uganda Virus Research Institute (UVRI) and London School of Hygiene & Tropical Medicine (LSHTM).  Biomedical Research and Training Instititute, Kintampo Health Research Centre, Haramaya University, MRC Unit The Gambia at LSHTM and Zambart are partners

Consortium Management Group
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Dr. Eugene

Ruzagira

UVRI

Lead work package 1, Scientific leadership

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LSHTM

Lead work package 2, CREATIVE coordination

Shirine is Director of Operations for the LSHTM Clinical Trials Unit (CTU). She works with the CTU co-directors to shape the strategic direction of the CTU and has oversight of all CTU operational activities, including trial management, data management, IT infrastructure and support, administration and compliance with regulatory and funder policies. She is keen to expand the support available to staff and partners involved in clinical trials across LSHTM and strengthen opportunities for exchange of best practice through the emerging LSHTM Clinical Trials Network. Prior to starting her current position in November 2022, Shirine spent six years at KEMRI Wellcome Trust Research Programme in Kilifi, Kenya. She worked as Programme Manager and Department Manager for the Epidemiology and Demography Department. During this time she also provided management oversight to the Hararghe Health Research Partnership in Eastern Ethiopia where she remains a member of the management team. Before moving to Kenya, Shirine worked as a Programme Manager for LSHTM in London and was responsible for the delivery of a portfolio of maternal, newborn and child health evaluation grants in Ethiopia, India and Nigeria. Shirine has a Doctorate in Public Health from LSHTM focused on Equitable Global Health Research Partnerships, an MSc in Management from Cranfield University and an MA in Natural Sciences from the University of Cambridge. Before joining LSHTM in 2011, Shirine worked for over a decade in organisation development, research management, grant management and operations at Ashridge Consulting, Ashridge Business School and English Nature.

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Dr. David

Macleod

LSHTM

Co-lead work package 3, Academic training & mentorship

David is an Associate Professor in Medical Statistics within the International Statistics and Epidemiology Group (ISEG) in the department of Infectious Disease Epidemiology & International Health (IDE-IH). He has a focus on large-scale trials and applied epidemiological research in global health, primarily in eye health and HIV prevention and treatment. He led the ISEG Fellowship programme for African medical statisticians from 2018-2024 and is currently the LSHTM lead as one of the northern partner institutions in the Sub-Saharan Africa Consortium for Advanced Biostatistics Training (SSACAB). David originally trained in Electronic and Electrical Engineering, going on to work in Telecommunications before retraining as a statistician in 2011 at LSHTM. He went on to obtain his PhD in Medical Statistics at LSHTM in 2016.

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Prof. Kwaku Poku Asante

KHRC

Co-lead work package 3, Academic training & mentorship

Prof. Kwaku Poku Asante, is a medical doctor and an epidemiologist. Currently, he is the Director of Kintampo Health Research Centre of the Research and Development Division of Ghana Health Service. With over twenty years’ experience in public health research, Prof. Asante has led numerous research projects as the lead investigator in several African Countries including Ghana, Burkina Faso, Kenya, Guinea, Malawi, Zambia and Uganda. He has received research grants from the Government of Ghana, EDCTP, WHO, Wellcome Trust, USAID, USA National Institute of Health, Global Alliance for Clean Cookstoves, Thrasher Research Fund, AngloGold Ashanti Malaria Control Program/ Global Fund, Bill and Melinda Gates Foundation, GSK Biologicals among others to conduct intervention and epidemiological studies in tropical diseases that have been used to influence health policy in Ghana and other developing countries. His research interest has been in the area of malaria and environmental health with over one hundred peer-reviewed publications and over forty students’ academic research work supervision from various universities locally and internationally. Prof. Asante holds a BSc, MD and MPH degrees from the University of Ghana and a PhD from the London School of Hygiene and Tropical Medicine.

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Dr. Thomas

Gyan

KHRC

Co-lead work package 3, Academic training & mentorship

Dr Gyan is a Deputy Chief Health Research Officer and an Epidemiologist with the Kintampo Health Research Centre (KHRC) of the Research and Development Division of Ghana Health Service. Dr Gyan is currently working as co-principal investigator and coordinating fellow of anongoing EDCTP funded Malaria Vaccine Pilot Evaluation Case-Control studies in Ghana, Kenya and Malawi. This was after a similar role in a just completed World Health Organization (WHO) funded malaria vaccine pilot evaluation (MVPE) study, that assessed the RTS,S/AS01 Malaria Vaccine Implementation Programme (MVIP) in Ghana. With over fifteen years’ experience in health research, Dr Gyan has led several other research projects as project manager or a coordinator. He has conducted and managed numerous largescale intervention and field epidemiological studies to influence policies in Ghana and beyond with other research grants from the Government of Ghana, Bill and Melinda Gates Foundation and the World Bank, among others. His research interest has been in the area of malaria, vaccines, maternal and child health, health systems research, training of early career researchers and project evaluation. He has over 30 peer-reviewed publications and supervises both local and international students who undertakes field research practical training at the Kintampo Health Research Centre. Dr Gyan holds a Bacholor’s degree from the University for Development Studies and a master’s degree in Public Health from the Kwame Nkrumah University of Science and Technology all in Ghana. This was followed by a PhD from the University of Western Australia, Perth Australia.

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Dr. Armel

Zemsi

MRCG at LSHTM

Lead work package 4, Work placement & integration

Dr. Armel Zemsi, MD, MSc (Clinical Trials) is a clinical trialist and global health researcher with extensive experience in the design, implementation, and oversight of clinical research in West Africa. He is the Head of the Clinical Trials Unit (CTU) at the Medical Research Council Unit The Gambia (MRCG) at LSHTM, where he leads a multidisciplinary team supporting Phase I–III clinical trials, with a particular focus on vaccines and infectious diseases. In addition to overseeing local trial operations, he directs regional monitoring and capacity strengthening initiatives across The Gambia, Nigeria, Liberia, Sierra Leone, and other West African countries. Dr. Zemsi has played a key role in major regional research capacity programmes, including CEPI-funded initiatives aimed at strengthening preparedness for Lassa fever vaccine trials and enhancing epidemic response readiness. His work bridges operational trial delivery, regulatory and pharmacovigilance oversight, and institutional capacity building. He has been instrumental in training Clinical Research Associates and clinical trial professionals across West Africa, contributing to the development of sustainable regional expertise in Good Clinical Practice (GCP)–compliant research. His research interests include informed consent processes in resource-limited settings, ethical conduct of clinical trials, quality management systems, and innovative approaches to improving participant understanding and trial oversight. Through his leadership, the CTU is evolving from a monitoring-focused unit into a strategic clinical development partner supporting sponsors, regulators, and academic institutions across the region. Dr. Zemsi is committed to advancing high-quality, ethically robust clinical research in Africa and to strengthening institutional systems that promote integrity, accountability, and long-term research sustainability.

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Prof. Katharina Kranzer

LSHTM/BRTI

Co-lead work package 5, Industry engagement

Katharina Kranzer is Professor of Infectious Disease Epidemiology in the Department of Clinical Research at the London School of Hygiene & Tropical Medicine (LSHTM), where she leads a multidisciplinary research programme focused on tuberculosis (TB), multimorbidity and health systems strengthening. She plays a central role in developing and leading large international research and capacity-building initiatives including a EDCTP funded research training network (SOFAR) with partner institutions in Zambia, Zimbabwe and Mozambique. She supervises doctoral and postdoctoral researchers, and contributes to institutional leadership and training programmes. She also serves as Director of the Health Research Unit Zimbabwe (THRU-Zim) at the Biomedical Research and Training Institute (BRTI), strengthening research partnerships, clinical research delivery and capacity development across southern Africa.Previously, she held a range of academic, clinical and leadership roles across Europe and Africa. These include Clinical Associate Professor at LSHTM, Clinical Director of the National and Supranational Tuberculosis Reference Laboratory in Germany, and senior scientist and group leader in mycobacterial diagnostics at the Research Centre Borstel. She has also worked extensively as a clinician-scientist in the UK and southern Africa. Her work has consistently combined clinical research, laboratory science and capacity strengthening in high TB-burden settings. She has served on multiple WHO TB guidelines groups and is the chair of the scientific conference committee of the The Union World Conference on Lung Health. Katharina trained in medicine at the Technical University of Munich and completed specialist clinical training in medical microbiology and virology in the UK. She holds multiple postgraduate qualifications from LSHTM, including an MSc in Tropical Medicine, an MSc in Epidemiology and a PhD in Epidemiology, as well as membership and fellowship of the Royal College of Physicians and Royal College of Pathologists. During her PhD studies which were focused on the role of active case finding and antiretroviral therapy on TB epidemiology in high TB-HIV burden settings she was based at the University of Cape Town. She has received numerous international awards for research and leadership in global health and tuberculosis, reflecting her longstanding commitment to training and collaborative research across Europe and Africa.

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Dr. Edson Marambire

BRTI

Co-lead work package 5, Industry engagement

Edson Marambire is a clinician-scientist, public health postdoctoral research fellow, and training and mentorship co-lead at the Health Research Unit at the Biomedical Research and Training Institute in Zimbabwe. Edson has extensive experience working within the health systems of Zimbabwe, where he has contributed to the implementation and evaluation of HIV and TB prevention and treatment services within the public sector and with international organisations. His career has a strong foundation in both clinical research and public health. His work is dedicated to addressing the complex challenges faced by vulnerable and underserved populations in resource-limited settings. A key aspect of his research is his deep engagement with affected communities. specialising in infectious disease dynamics and health systems in low- and middle-income countries (LMICs). Edson’s career is built upon a strong clinical foundation, having begun my journey as a nurse (BSc Nursing Science, University of Zimbabwe, 2009) and later advancing through a Master of Public Health and a PhD in International Health (LMU Munich, 2025). His primary scientific focus is on TB transmission and integrated care delivery within high-burden settings.

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Dr. Modupe Amofa-Sekyi

Zambart

Co-lead work package 6, Network development

Dr Modupe Amofa-Sekyi is a clinician scientist at Zambart, a multi-disciplinary non-profit public health research organization in Zambia. She is currently involved with the M72 TB candidate vaccine trial as a sub-investigator where she is responsible for providing leadership and guidance to study staff; ensuring that all regulatory standards are upheld at all times always upheld and that the study is conducted in accordance with GCP, international and in-country guidelines and regulations. She has18 years of clinical and health research experience. She has been involved in designing and designing and conducting epidemiological conducting epidemiological research studies as well as supervised different study teams and teams and maintain overall study oversight. She has worked closely with the Ministry of Health and other stakeholders implementing stakeholders implementing TB/HIV activities in Zambia. Dr Modupe Amofa-Sekyi holds a BSc. Medical Sciences from the University of Ghana, MB ChB from the University of Ghana, MSc Vaccinology & Clinical Pharmaceutical Development from University of Siena, Italy, and a PhD Clinical Research from the London School of Hygiene and Tropical Medicine, University of London.

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Dr. Nega Assefa

Haramaya University

Co-lead work package 6, Network development

Prof. Nega Assefa (PhD) is Professor of Maternal and Child Health at College of Health and Medical Sciences, Haramaya University, where he has served since 1993.He previously held senior leadership positions as Chief Executive Director of the College of Health and Medical Sciences and as Director for Research Groups and Partnerships Directorate at Haramaya University. He established and led Hararghe Health and Demographic Surveillance System (HDSS) under Haramaya University for more than 12 years. Since 2017, Prof. Nega has led the inception and ongoing work of Hararghe Health Research (HHR), partnership between Haramaya University and London School of Hygiene & Tropical Medicine (LSHTM). He currently holds appointments as Honorary Associate Professor at LSHTM, Consultant Associate Professor at Harvard T.H. Chan School of Public Health and is a member of the Federal Ministry of Health’s Maternal and Child Health Advisory Group. His research focuses on pregnancy and childbirth, family planning, child growth and development, and child survival. He has published 226 peer-reviewed articles and secured 11 research grants. Prof. Nega has supervised 19 PhD students and more than 215 master’s students, including candidates from University of Durban (South Africa), Ghana, LSHTM, and Haramaya University. This supervisory work has been carried out in partnership with fellows from institutions including Johns Hopkins Bloomberg School of Public Health, Harvard T.H. Chan School of Public Health, LSHTM, Emory University’s Global Health Institute, Karolinska Institute, and University of Vienna. In 2024, he received Lifetime Distinguished Professional Service Award from Ethiopia’s Federal Ministry of Health in recognition of his significant achievements and longstanding commitment to public health.

The Consortium Management Group (CMG) is responsible for delivering CREATIVE, ensuring a seamless and high-quality experience for Fellows that fulfils all programme objectives.  Each partner leads one of CREATIVE’s six work packages (WP)  and is represented on the CMG.

Joint Advisory Committee

JOINT ADVISORY COMMITTEE

A strategic Advisory Committee provides independent oversight of CREATIVE’s progress and offers advice to strengthen the programme, overcome challenges and achieve long-term impact. All members have extensive experience covering different aspects of the programme.  The committee jointly advises on CREATIVE and its sister programme, the Creating Opportunities for Master’s Programmes for Africa: Support and Scholarships (COMPASS) fellowship scheme, also funded by EDCTP.

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Dr. Paul Ndaya-Oloo

Coalition for Epidemic Preparedness Innovations (CEPI)

Senior Clinical Development Lead

Paul Oloo is a Senior Clinical Development Lead at the Coalition for Epidemic Preparedness Innovations (CEPI), based in London, United Kingdom. A trained medical doctor with an Executive MSc in Vaccinology and Pharmaceutical Clinical Development (University of Siena), he brings extensive experience across vaccine and therapeutic development, with a focus on advancing early-stage and late-stage clinical strategies and strengthening clinical research systems. He plays a key role in accelerating outbreak preparedness and equitable access to medical countermeasures, while strengthening clinical research ecosystems. His work has contributed to building clinical trial capacity and developing research scientists across Africa, supporting sustainable, high-quality trial delivery in outbreak and peace-time settings. Known for his collaborative leadership, he effectively brings together multidisciplinary teams and stakeholders to drive complex clinical development initiatives forward.

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Prof. Emily Webb

LSHTM

​Professor of Medical Statistics and Epidemiology,

Strategic Advisory Committee chair

I am Director of the MRC International Statistics and Epidemiology Group (ISEG), and am co-theme leader for ISEG's work on emerging and neglected diseases. My current research focuses on the design and analysis of intervention and observational studies in the fields of helminths, vaccines and child health, with a particular interest in cluster randomised trials. I lead capacity strengthening programmes in epidemiology and medical statistics for scientists from sub-Saharan Africa.

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Dr. Tobias

Chirwa

University of the Witwatersrand

​Head of School of Public Health

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Dr. Opokua Ofori-Anyinam

GlaxoSmithKline (GSK)

​Director Clinical Development

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